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Extracellular and Luminal pH Regulation by Vacuolar H(+)-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes
Plasma membrane vacuolar H(+)-ATPase (V-ATPase) activity of tumor cells is a major factor in control of cytoplasmic and extracellular pH and metastatic potential, but the isoforms involved and the factors governing plasma membrane recruitment remain uncertain. Here, we examined expression, distribut...
Autores principales: | Smith, Gina A., Howell, Gareth J., Phillips, Clair, Muench, Stephen P., Ponnambalam, Sreenivasan, Harrison, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861423/ https://www.ncbi.nlm.nih.gov/pubmed/26912656 http://dx.doi.org/10.1074/jbc.M116.723395 |
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