Germ Cell Nuclear Factor (GCNF) Represses Oct4 Expression and Globally Modulates Gene Expression in Human Embryonic Stem (hES) Cells

Oct4 is considered a key transcription factor for pluripotent stem cell self-renewal. It binds to specific regions within target genes to regulate their expression and is downregulated upon induction of differentiation of pluripotent stem cells; however, the mechanisms that regulate the levels of hu...

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Detalles Bibliográficos
Autores principales: Wang, Hongran, Wang, Xiaohong, Xu, Xueping, Kyba, Michael, Cooney, Austin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861434/
https://www.ncbi.nlm.nih.gov/pubmed/26769970
http://dx.doi.org/10.1074/jbc.M115.694208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861434/
https://www.ncbi.nlm.nih.gov/pubmed/26769970
http://dx.doi.org/10.1074/jbc.M115.694208

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