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Germ Cell Nuclear Factor (GCNF) Represses Oct4 Expression and Globally Modulates Gene Expression in Human Embryonic Stem (hES) Cells

Oct4 is considered a key transcription factor for pluripotent stem cell self-renewal. It binds to specific regions within target genes to regulate their expression and is downregulated upon induction of differentiation of pluripotent stem cells; however, the mechanisms that regulate the levels of hu...

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Detalles Bibliográficos
Autores principales:	Wang, Hongran, Wang, Xiaohong, Xu, Xueping, Kyba, Michael, Cooney, Austin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861434/ https://www.ncbi.nlm.nih.gov/pubmed/26769970 http://dx.doi.org/10.1074/jbc.M115.694208

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