Cargando…
The Luminescent Oligothiophene p-FTAA Converts Toxic Aβ(1–42) Species into Nontoxic Amyloid Fibers with Altered Properties
Aggregation of the amyloid-β peptide (Aβ) in the brain leads to the formation of extracellular amyloid plaques, which is one of the pathological hallmarks of Alzheimer disease (AD). It is a general hypothesis that soluble prefibrillar assemblies of the Aβ peptide, rather than mature amyloid fibrils,...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861488/ https://www.ncbi.nlm.nih.gov/pubmed/26907684 http://dx.doi.org/10.1074/jbc.M115.696229 |