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Functional Evolution in Orthologous Cell-encoded RNA-dependent RNA Polymerases

Many eukaryotic organisms encode more than one RNA-dependent RNA polymerase (RdRP) that probably emerged as a result of gene duplication. Such RdRP paralogs often participate in distinct RNA silencing pathways and show characteristic repertoires of enzymatic activities in vitro. However, to what ext...

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Detalles Bibliográficos
Autores principales: Qian, Xinlei, Hamid, Fursham M., El Sahili, Abbas, Darwis, Dina Amallia, Wong, Yee Hwa, Bhushan, Shashi, Makeyev, Eugene V., Lescar, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861493/
https://www.ncbi.nlm.nih.gov/pubmed/26907693
http://dx.doi.org/10.1074/jbc.M115.685933