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IL-6/STAT3 signaling in mice with dysfunctional type-2 ryanodine receptor

Mice with genetically modified cardiac ryanodine receptor (Ryr2(ADA/ADA) mice) are impaired in regulation by calmodulin, develop severe cardiac hypertrophy and die about 2 weeks after birth. We hypothesized that the interleukin 6 (IL-6)/signal transducer and activator of transcription-3 (STAT3) sign...

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Detalles Bibliográficos
Autores principales: Huang, Tai-Qin, Willis, Monte S, Meissner, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861591/
https://www.ncbi.nlm.nih.gov/pubmed/27217982
http://dx.doi.org/10.1080/21623996.2016.1158379