Cargando…

N-Terminal Ile-Orn- and Trp-Orn-Motif Repeats Enhance Membrane Interaction and Increase the Antimicrobial Activity of Apidaecins against Pseudomonas aeruginosa

The Gram-negative bacterium Pseudomonas aeruginosa is a life-threatening nosocomial pathogen due to its generally low susceptibility toward antibiotics. Furthermore, many strains have acquired resistance mechanisms requiring new antimicrobials with novel mechanisms to enhance treatment options. Prol...

Descripción completa

Detalles Bibliográficos
Autores principales: Bluhm, Martina E. C., Schneider, Viktoria A. F., Schäfer, Ingo, Piantavigna, Stefania, Goldbach, Tina, Knappe, Daniel, Seibel, Peter, Martin, Lisandra L., Veldhuizen, Edwin J. A., Hoffmann, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861708/
https://www.ncbi.nlm.nih.gov/pubmed/27243004
http://dx.doi.org/10.3389/fcell.2016.00039