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Anti-Cancer Stem-like Cell Compounds in Clinical Development – An Overview and Critical Appraisal

Cancer stem-like cells (CSC) represent a subpopulation of tumor cells with elevated tumor-initiating potential. Upon differentiation, they replenish the bulk of the tumor cell population. Enhanced tumor-forming capacity, resistance to antitumor drugs, and metastasis-forming potential are the hallmar...

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Detalles Bibliográficos
Autores principales: Marcucci, Fabrizio, Rumio, Cristiano, Lefoulon, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861739/
https://www.ncbi.nlm.nih.gov/pubmed/27242955
http://dx.doi.org/10.3389/fonc.2016.00115