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Anti-Cancer Stem-like Cell Compounds in Clinical Development – An Overview and Critical Appraisal
Cancer stem-like cells (CSC) represent a subpopulation of tumor cells with elevated tumor-initiating potential. Upon differentiation, they replenish the bulk of the tumor cell population. Enhanced tumor-forming capacity, resistance to antitumor drugs, and metastasis-forming potential are the hallmar...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861739/ https://www.ncbi.nlm.nih.gov/pubmed/27242955 http://dx.doi.org/10.3389/fonc.2016.00115 |