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Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery

In the human genome more than 400 genes encode ion channels, which are transmembrane proteins mediating ion fluxes across membranes. Being expressed in all cell types, they are involved in almost all physiological processes, including sense perception, neurotransmission, muscle contraction, secretio...

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Detalles Bibliográficos
Autores principales: Imbrici, Paola, Liantonio, Antonella, Camerino, Giulia M., De Bellis, Michela, Camerino, Claudia, Mele, Antonietta, Giustino, Arcangela, Pierno, Sabata, De Luca, Annamaria, Tricarico, Domenico, Desaphy, Jean-Francois, Conte, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861771/
https://www.ncbi.nlm.nih.gov/pubmed/27242528
http://dx.doi.org/10.3389/fphar.2016.00121