Scaffolded Antigens in Yeast Cell Particle Vaccines Provide Protection against Systemic Polyoma Virus Infection

Background. U65, a self-aggregating peptide scaffold, traps fused protein antigens in yeast cells. Conversion to Yeast Cell Particle (YCP) vaccines by partial removal of surface mannoproteins exposes β-glucan, mediating efficient uptake by antigen-presenting cells (APCs). YCP vaccines are inexpensiv...

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Detalles Bibliográficos
Autores principales: Tipper, Donald J., Szomolanyi-Tsuda, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861779/
https://www.ncbi.nlm.nih.gov/pubmed/27213160
http://dx.doi.org/10.1155/2016/2743292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861779/
https://www.ncbi.nlm.nih.gov/pubmed/27213160
http://dx.doi.org/10.1155/2016/2743292

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