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Differential DNA Methylation of MicroRNA Genes in Temporal Cortex from Alzheimer's Disease Individuals

This study investigated for the first time the genomewide DNA methylation changes of noncoding RNA genes in the temporal cortex samples from individuals with Alzheimer's disease (AD). The methylome of 10 AD individuals and 10 age-matched controls were obtained using Illumina 450 K methylation a...

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Detalles Bibliográficos
Autores principales: Villela, Darine, Ramalho, Rodrigo F., Silva, Aderbal R. T., Brentani, Helena, Suemoto, Claudia K., Pasqualucci, Carlos Augusto, Grinberg, Lea T., Krepischi, Ana C. V., Rosenberg, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861808/
https://www.ncbi.nlm.nih.gov/pubmed/27213057
http://dx.doi.org/10.1155/2016/2584940