Synthesis of a highly water-soluble acacetin prodrug for treating experimental atrial fibrillation in beagle dogs

We previously reported that duodenal administration of the natural flavone acacetin can effectively prevent the induction of experimental atrial fibrillation (AF) in canines; however, it may not be used intravenously to terminate AF due to its poor water-solubility. The present study was to design a...

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Detalles Bibliográficos
Autores principales: Liu, Hui, Wang, Ya-Jing, Yang, Lei, Zhou, Mei, Jin, Man-Wen, Xiao, Guo-Sheng, Wang, Yan, Sun, Hai-Ying, Li, Gui-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861903/
https://www.ncbi.nlm.nih.gov/pubmed/27160397
http://dx.doi.org/10.1038/srep25743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861903/
https://www.ncbi.nlm.nih.gov/pubmed/27160397
http://dx.doi.org/10.1038/srep25743

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