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Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells

BACKGROUND: Triple negative breast cancer (TNBC) is a highly heterogeneous and aggressive type of cancer that lacks effective targeted therapy. Despite detailed molecular profiling, no targeted therapy has been established. Hence, with the aim of gaining deeper understanding of the functional differ...

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Detalles Bibliográficos
Autores principales: Gautam, Prson, Karhinen, Leena, Szwajda, Agnieszka, Jha, Sawan Kumar, Yadav, Bhagwan, Aittokallio, Tero, Wennerberg, Krister
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862054/
https://www.ncbi.nlm.nih.gov/pubmed/27165605
http://dx.doi.org/10.1186/s12943-016-0517-3