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Enhanced replication of avian-origin H3N2 canine influenza virus in eggs, cell cultures and mice by a two-amino acid insertion in neuraminidase stalk

Canine influenza virus (CIV) is a newly identified, highly contagious respiratory pathogen in dogs. Recent studies indicate that avian-origin H3N2 CIV are circulating in Chinese dogs. To investigate the effects of a two-amino acid (2-aa) insertion naturally occurring at the distal end of the neurami...

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Detalles Bibliográficos
Autores principales: Lin, Yan, Xie, Xing, Zhao, Yanbing, Kalhoro, Dildar Hussain, Lu, Chengping, Liu, Yongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862097/
https://www.ncbi.nlm.nih.gov/pubmed/27160077
http://dx.doi.org/10.1186/s13567-016-0337-x