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Distinct epigenetic features of differentiation-regulated replication origins

BACKGROUND: Eukaryotic genome duplication starts at discrete sequences (replication origins) that coordinate cell cycle progression, ensure genomic stability and modulate gene expression. Origins share some sequence features, but their activity also responds to changes in transcription and cellular...

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Detalles Bibliográficos
Autores principales: Smith, Owen K., Kim, RyanGuk, Fu, Haiqing, Martin, Melvenia M., Lin, Chii Mei, Utani, Koichi, Zhang, Ya, Marks, Anna B., Lalande, Marc, Chamberlain, Stormy, Libbrecht, Maxwell W., Bouhassira, Eric E., Ryan, Michael C., Noble, William S., Aladjem, Mirit I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862150/
https://www.ncbi.nlm.nih.gov/pubmed/27168766
http://dx.doi.org/10.1186/s13072-016-0067-3