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Distinct epigenetic features of differentiation-regulated replication origins
BACKGROUND: Eukaryotic genome duplication starts at discrete sequences (replication origins) that coordinate cell cycle progression, ensure genomic stability and modulate gene expression. Origins share some sequence features, but their activity also responds to changes in transcription and cellular...
Autores principales: | Smith, Owen K., Kim, RyanGuk, Fu, Haiqing, Martin, Melvenia M., Lin, Chii Mei, Utani, Koichi, Zhang, Ya, Marks, Anna B., Lalande, Marc, Chamberlain, Stormy, Libbrecht, Maxwell W., Bouhassira, Eric E., Ryan, Michael C., Noble, William S., Aladjem, Mirit I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862150/ https://www.ncbi.nlm.nih.gov/pubmed/27168766 http://dx.doi.org/10.1186/s13072-016-0067-3 |
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