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Detecting and correcting the binding-affinity bias in ChIP-seq data using inter-species information

BACKGROUND: Transcriptional gene regulation is a fundamental process in nature, and the experimental and computational investigation of DNA binding motifs and their binding sites is a prerequisite for elucidating this process. ChIP-seq has become the major technology to uncover genomic regions conta...

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Detalles Bibliográficos
Autores principales: Nettling, Martin, Treutler, Hendrik, Cerquides, Jesus, Grosse, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862171/
https://www.ncbi.nlm.nih.gov/pubmed/27165633
http://dx.doi.org/10.1186/s12864-016-2682-6