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Detecting and correcting the binding-affinity bias in ChIP-seq data using inter-species information
BACKGROUND: Transcriptional gene regulation is a fundamental process in nature, and the experimental and computational investigation of DNA binding motifs and their binding sites is a prerequisite for elucidating this process. ChIP-seq has become the major technology to uncover genomic regions conta...
Autores principales: | Nettling, Martin, Treutler, Hendrik, Cerquides, Jesus, Grosse, Ivo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862171/ https://www.ncbi.nlm.nih.gov/pubmed/27165633 http://dx.doi.org/10.1186/s12864-016-2682-6 |
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