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Estimation of ribosome profiling performance and reproducibility at various levels of resolution

BACKGROUND: Ribosome profiling (or Ribo-seq) is currently the most popular methodology for studying translation; it has been employed in recent years to decipher various fundamental gene expression regulation aspects. The main promise of the approach is its ability to detect ribosome densities over...

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Detalles Bibliográficos
Autores principales: Diament, Alon, Tuller, Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862193/
https://www.ncbi.nlm.nih.gov/pubmed/27160013
http://dx.doi.org/10.1186/s13062-016-0127-4