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RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell border

Endothelial barrier dysfunction underlies chronic inflammatory diseases. In searching for new proteins essential to the human endothelial inflammatory response, we have found that the endosomal GTPase RhoB is up-regulated in response to inflammatory cytokines and expressed in the endothelium of some...

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Detalles Bibliográficos
Autores principales: Marcos-Ramiro, Beatriz, García-Weber, Diego, Barroso, Susana, Feito, Jorge, Ortega, María C., Cernuda-Morollón, Eva, Reglero-Real, Natalia, Fernández-Martín, Laura, Durán, Maria C., Alonso, Miguel A., Correas, Isabel, Cox, Susan, Ridley, Anne J., Millán, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862328/
https://www.ncbi.nlm.nih.gov/pubmed/27138256
http://dx.doi.org/10.1083/jcb.201504038