Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C

Enteroviruses (EVs) represent many important pathogens of humans. Unfortunately, no antiviral compounds currently exist to treat infections with these viruses. We screened the Prestwick Chemical Library, a library of approved drugs, for inhibitors of coxsackievirus B3, identified pirlindole as a pot...

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Detalles Bibliográficos
Autores principales: Ulferts, Rachel, de Boer, S. Matthijn, van der Linden, Lonneke, Bauer, Lisa, Lyoo, Hey Rhyoung, Maté, Maria J., Lichière, Julie, Canard, Bruno, Lelieveld, Daphne, Omta, Wienand, Egan, David, Coutard, Bruno, van Kuppeveld, Frank J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862474/
https://www.ncbi.nlm.nih.gov/pubmed/26856848
http://dx.doi.org/10.1128/AAC.02182-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862474/
https://www.ncbi.nlm.nih.gov/pubmed/26856848
http://dx.doi.org/10.1128/AAC.02182-15

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