Cargando…

T cell ignorance is bliss: T cells are not tolerized by Langerhans cells presenting human papillomavirus antigens in the absence of costimulation

Human papillomavirus type 16 (HPV16) infections are intra-epithelial, and thus, HPV16 is known to interact with Langerhans cells (LCs), the resident epithelial antigen-presenting cells (APCs). The current paradigm for APC-mediated induction of T cell anergy is through delivery of T cell receptor sig...

Descripción completa

Detalles Bibliográficos
Autores principales: Woodham, Andrew W., Yan, Lisa, Skeate, Joseph G., van der Veen, Daniel, Brand, Heike E., Wong, Michael K., Da Silva, Diane M., Kast, W. Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862606/
https://www.ncbi.nlm.nih.gov/pubmed/27182559
http://dx.doi.org/10.1016/j.pvr.2016.01.002