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Environmentally induced epigenetic transgenerational inheritance of altered SRY genomic binding during gonadal sex determination

A critical transcription factor required for mammalian male sex determination is sex determining region on the Y chromosome (SRY). The expression of SRY in precursor Sertoli cells is one of the initial events in testis development. This study was designed to determine the impact of environmentally i...

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Detalles Bibliográficos
Autores principales: Skinner, Michael K., Bhandari, Ramji K., Haque, M. Muksitul, Nilsson, Eric E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862609/
https://www.ncbi.nlm.nih.gov/pubmed/27175298
http://dx.doi.org/10.1093/eep/dvv004