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Environmentally induced epigenetic transgenerational inheritance of altered SRY genomic binding during gonadal sex determination
A critical transcription factor required for mammalian male sex determination is sex determining region on the Y chromosome (SRY). The expression of SRY in precursor Sertoli cells is one of the initial events in testis development. This study was designed to determine the impact of environmentally i...
Autores principales: | Skinner, Michael K., Bhandari, Ramji K., Haque, M. Muksitul, Nilsson, Eric E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862609/ https://www.ncbi.nlm.nih.gov/pubmed/27175298 http://dx.doi.org/10.1093/eep/dvv004 |
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