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Comparison of Intranasal Outer Membrane Vesicles with Cholera Toxin and Injected MF59C.1 as Adjuvants for Malaria Transmission Blocking Antigens AnAPN1 and Pfs48/45

Purified protein vaccines often require adjuvants for efficient stimulation of immune responses. There is no licensed mucosal adjuvant on the market to adequately boost the immune response to purified antigens for intranasal applications in humans. Bacterial outer membrane vesicles (OMV) are attract...

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Detalles Bibliográficos
Autores principales: Pritsch, Michael, Ben-Khaled, Najib, Chaloupka, Michael, Kobold, Sebastian, Berens-Riha, Nicole, Peter, Annabell, Liegl, Gabriele, Schubert, Sören, Hoelscher, Michael, Löscher, Thomas, Wieser, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863099/
https://www.ncbi.nlm.nih.gov/pubmed/27239480
http://dx.doi.org/10.1155/2016/3576028