Extracellular acidification stimulates GPR68 mediated IL-8 production in human pancreatic β cells

Acute or chronic metabolic complications such as diabetic ketoacidosis are often associated with extracellular acidification and pancreatic β-cell dysfunction. However, the mechanisms by which human β-cells sense and respond to acidic pH remain elusive. In this study, using the recently developed hu...

Descripción completa

Detalles Bibliográficos
Autores principales: Chandra, Vikash, Karamitri, Angeliki, Richards, Paul, Cormier, Françoise, Ramond, Cyrille, Jockers, Ralf, Armanet, Mathieu, Albagli-Curiel, Olivier, Scharfmann, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863151/
https://www.ncbi.nlm.nih.gov/pubmed/27166427
http://dx.doi.org/10.1038/srep25765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863151/
https://www.ncbi.nlm.nih.gov/pubmed/27166427
http://dx.doi.org/10.1038/srep25765

Ejemplares similares