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Extracellular acidification stimulates GPR68 mediated IL-8 production in human pancreatic β cells

Acute or chronic metabolic complications such as diabetic ketoacidosis are often associated with extracellular acidification and pancreatic β-cell dysfunction. However, the mechanisms by which human β-cells sense and respond to acidic pH remain elusive. In this study, using the recently developed hu...

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Detalles Bibliográficos
Autores principales:	Chandra, Vikash, Karamitri, Angeliki, Richards, Paul, Cormier, Françoise, Ramond, Cyrille, Jockers, Ralf, Armanet, Mathieu, Albagli-Curiel, Olivier, Scharfmann, Raphael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863151/ https://www.ncbi.nlm.nih.gov/pubmed/27166427 http://dx.doi.org/10.1038/srep25765

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