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Sex differences in the serum level of endogenous ligands for estrogen receptor β in the elderly population

Animal studies suggest that estrogen receptor β (ERβ)-agonists, but not ERα-agonists, are antidepressants. Several endogenous ligands for ERβ have been proposed, including 5α-androstane-3β, 17β-diol (3βAdiol), Androstenediol (Δ5-diol), and 7α-hydroxydehydroepiandrosterone (7α-OH-DHEA). The aim of th...

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Detalles Bibliográficos
Autores principales: Kobayashi, Miyuki, Sugiyama, Nobuhiro, Sasayama, Daimei, Sasamoto, Hidehiko, Miyashiro, Yoshimichi, Arima, Kunimasa, Washizuka, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863166/
https://www.ncbi.nlm.nih.gov/pubmed/27165125
http://dx.doi.org/10.1038/srep25878