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AAV-Mediated Transduction and Targeting of Retinal Bipolar Cells with Improved mGluR6 Promoters in Rodents and Primates

Adeno-associated virus (AAV) vectors have been a powerful gene delivery vehicle to the retina for basic research and gene therapy. For many of these applications, achieving cell-type specific targeting and high transduction efficiency is desired. Recently, there has been increasing interest in AAV-m...

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Detalles Bibliográficos
Autores principales: Lu, Q, Ganjawala, TH, Ivanova, E, Cheng, JG, Troilo, D, Pan, Z-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863234/
https://www.ncbi.nlm.nih.gov/pubmed/27115727
http://dx.doi.org/10.1038/gt.2016.42