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Functional role of the nicotinic arm of the acetylcholine regulatory axis in human B-cell lines

We studied the involvement of nicotinic acetylcholine receptors (nAChRs) in the inflammation-related activity of human B-cell lines. Activation of nAChRs in Daudi cells with epibatidine abolished the pansorbin-dependent upregulation of the pro-inflammatory marker Cox-2 both at the mRNA and protein l...

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Detalles Bibliográficos
Autores principales: Arredondo, Juan, Omelchenko, Denys, Chernyavsky, Alexander I, Qian, Jing, Skok, Maryna, Grando, Sergei A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863279/
https://www.ncbi.nlm.nih.gov/pubmed/27186084