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Diversity-oriented natural product platform identifies plant constituents targeting Plasmodium falciparum

BACKGROUND: A diverse library of pre-fractionated plant extracts, generated by an automated high-throughput system, was tested using an in vitro anti-malarial screening platform to identify known or new natural products for lead development. The platform identifies hits on the basis of in vitro grow...

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Detalles Bibliográficos
Autores principales: Zhang, Jin, Bowling, John J., Smithson, David, Clark, Julie, Jacob, Melissa R., Khan, Shabana I., Tekwani, Babu L., Connelly, Michele, Samoylenko, Vladimir, Ibrahim, Mohamed A., Zaki, Mohamed A., Wang, Mei, Hester, John P., Tu, Ying, Jeffries, Cynthia, Twarog, Nathaniel, Shelat, Anang A., Walker, Larry A., Muhammad, Ilias, Guy, R. Kiplin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863362/
https://www.ncbi.nlm.nih.gov/pubmed/27165106
http://dx.doi.org/10.1186/s12936-016-1313-7