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Diversity-oriented natural product platform identifies plant constituents targeting Plasmodium falciparum
BACKGROUND: A diverse library of pre-fractionated plant extracts, generated by an automated high-throughput system, was tested using an in vitro anti-malarial screening platform to identify known or new natural products for lead development. The platform identifies hits on the basis of in vitro grow...
Autores principales: | Zhang, Jin, Bowling, John J., Smithson, David, Clark, Julie, Jacob, Melissa R., Khan, Shabana I., Tekwani, Babu L., Connelly, Michele, Samoylenko, Vladimir, Ibrahim, Mohamed A., Zaki, Mohamed A., Wang, Mei, Hester, John P., Tu, Ying, Jeffries, Cynthia, Twarog, Nathaniel, Shelat, Anang A., Walker, Larry A., Muhammad, Ilias, Guy, R. Kiplin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863362/ https://www.ncbi.nlm.nih.gov/pubmed/27165106 http://dx.doi.org/10.1186/s12936-016-1313-7 |
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