Diversity of breakpoints of variant Philadelphia chromosomes in chronic myeloid leukemia in Brazilian patients

BACKGROUND: Chronic myeloid leukemia is a myeloproliferative disorder characterized by the Philadelphia chromosome or t(9;22)(q34.1;q11.2), resulting in the break-point cluster region-Abelson tyrosine kinase fusion gene, which encodes a constitutively active tyrosine kinase protein. The Philadelphia...

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Detalles Bibliográficos
Autores principales: Chauffaille, Maria de Lourdes Lopes Ferrari, Bandeira, Ana Carolina de Almeida, da Silva, Aline Schiavoni Guarnieri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863423/
https://www.ncbi.nlm.nih.gov/pubmed/25638762
http://dx.doi.org/10.1016/j.bjhh.2014.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863423/
https://www.ncbi.nlm.nih.gov/pubmed/25638762
http://dx.doi.org/10.1016/j.bjhh.2014.07.006

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