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Single exposure of dopamine D1 antagonist prevents and D2 antagonist attenuates methylphenidate effect

Methylphenidate (MPD) is a readily prescribed drug for the treatment of attention deficit hyperactivity disorder (ADHD) and moreover is used illicitly by youths for its cognitive-enhancing effects and recreation. MPD exposure in rodents elicits increased locomotor activity. Repetitive MPD exposure l...

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Detalles Bibliográficos
Autores principales: Claussen, Catherine M, Witte, Lindsey J, Dafny, Nachum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863529/
https://www.ncbi.nlm.nih.gov/pubmed/27186140
http://dx.doi.org/10.2147/JEP.S75300