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Ouabain inhibits monocyte activation in vitro: prevention of the proinflammatory mCD14(+)/CD16(+) subset appearance and cell-size progression

Classically described as a potent inhibitor of the sodium-potassium adenosine triphosphatase enzyme, ouabain has been further shown to act as an effective immunomodulator in mammals. Recently, our group showed that this hormone downregulates membrane CD14 (mCD14) in human monocytes, though it is not...

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Detalles Bibliográficos
Autores principales: Valente, Raphael C, Araujo, Elizabeth G, Rumjanek, Vivian M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863552/
https://www.ncbi.nlm.nih.gov/pubmed/27186125
http://dx.doi.org/10.2147/JEP.S35507