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RbdB, a Rhomboid Protease Critical for SREBP Activation and Virulence in Aspergillus fumigatus

SREBP transcription factors play a critical role in fungal virulence; however, the mechanisms of sterol regulatory element binding protein (SREBP) activation in pathogenic fungi remains ill-defined. Screening of the Neurospora crassa whole-genome deletion collection for genes involved in hypoxia res...

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Detalles Bibliográficos
Autores principales: Dhingra, Sourabh, Kowlaski, Caitlin H., Thammahong, Arsa, Beattie, Sarah R., Bultman, Katherine M., Cramer, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863583/
https://www.ncbi.nlm.nih.gov/pubmed/27303716
http://dx.doi.org/10.1128/mSphere.00035-16