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The Rhoptry Pseudokinase ROP54 Modulates Toxoplasma gondii Virulence and Host GBP2 Loading

Toxoplasma gondii uses unique secretory organelles called rhoptries to inject an array of effector proteins into the host cytoplasm that hijack host cell functions. We have discovered a novel rhoptry pseudokinase effector, ROP54, which is injected into the host cell upon invasion and traffics to the...

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Detalles Bibliográficos
Autores principales: Kim, Elliot W., Nadipuram, Santhosh M., Tetlow, Ashley L., Barshop, William D., Liu, Philip T., Wohlschlegel, James A., Bradley, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863586/
https://www.ncbi.nlm.nih.gov/pubmed/27303719
http://dx.doi.org/10.1128/mSphere.00045-16