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Epidemic Keratoconjunctivitis-Causing Adenoviruses Induce MUC16 Ectodomain Release To Infect Ocular Surface Epithelial Cells

Human adenoviruses (HAdV), species D in particular (HAdV-D), are frequently associated with epidemic keratoconjunctivitis (EKC). Although the infection originates at the ocular surface epithelium, the mechanisms by which HAdV-Ds bypass the membrane-associated mucin (MAM)-rich glycocalyx of the ocula...

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Detalles Bibliográficos
Autores principales: Menon, Balaraj B., Zhou, Xiaohong, Spurr-Michaud, Sandra, Rajaiya, Jaya, Chodosh, James, Gipson, Ilene K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863608/
https://www.ncbi.nlm.nih.gov/pubmed/27303700
http://dx.doi.org/10.1128/mSphere.00112-15