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Model for the Controlled Synthesis of O-Antigen Repeat Units Involving the WaaL Ligase

The Wzx/Wzy O-antigen pathway involves synthesis of a repeat unit (O unit) consisting of 3 to 8 sugars on an inner-membrane-embedded lipid carrier. These O units are translocated across the membrane to its periplasmic face by Wzx, while retaining linkage to the carrier, and then polymerized by Wzy t...

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Detalles Bibliográficos
Autores principales: Hong, Yaoqin, Reeves, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863624/
https://www.ncbi.nlm.nih.gov/pubmed/27303678
http://dx.doi.org/10.1128/mSphere.00074-15