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Synergistic inhibition of colon cancer cell growth with nanoemulsion-loaded paclitaxel and PI3K/mTOR dual inhibitor BEZ235 through apoptosis

Colon cancer is the third most common cancer in the world, with drug resistance and metastasis being the major challenges to effective treatments. To overcome this, combination therapy with different chemotherapeutics is a common practice. In this study, we demonstrated that paclitaxel (PTX) togethe...

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Detalles Bibliográficos
Autores principales: Zou, Hong, Li, Li, Garcia Carcedo, Ines, Xu, Zhi Ping, Monteiro, Michael, Gu, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863683/
https://www.ncbi.nlm.nih.gov/pubmed/27226714
http://dx.doi.org/10.2147/IJN.S100744