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Theaflavin-3, 3′-digallate induces apoptosis and G2 cell cycle arrest through the Akt/MDM2/p53 pathway in cisplatin-resistant ovarian cancer A2780/CP70 cells

Ovarian cancer is the most lethal gynecological cancer among women worldwide. Adverse side effects and acquired resistance to conventional platinum based chemotherapy are major impediments in ovarian cancer treatment, and drive the development of more selective anticancer drugs that target cancer-sp...

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Detalles Bibliográficos
Autores principales: TU, YOUYING, KIM, EUNHYE, GAO, YING, RANKIN, GARY O., LI, BO, CHEN, YI CHARLIE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863729/
https://www.ncbi.nlm.nih.gov/pubmed/27082635
http://dx.doi.org/10.3892/ijo.2016.3472