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The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells

An open and decondensed chromatin organization is a defining property of pluripotency. Several epigenetic regulators have been implicated in maintaining an open chromatin organization, but how these processes are connected to the pluripotency network is unknown. Here, we identified a new role for th...

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Detalles Bibliográficos
Autores principales: Novo, Clara Lopes, Tang, Calvin, Ahmed, Kashif, Djuric, Ugljesa, Fussner, Eden, Mullin, Nicholas P., Morgan, Natasha P., Hayre, Jasvinder, Sienerth, Arnold R., Elderkin, Sarah, Nishinakamura, Ryuichi, Chambers, Ian, Ellis, James, Bazett-Jones, David P., Rugg-Gunn, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863740/
https://www.ncbi.nlm.nih.gov/pubmed/27125671
http://dx.doi.org/10.1101/gad.275685.115