Absence of UCHL 1 function leads to selective motor neuropathy

OBJECTIVE: The aim of this study was to investigate the role of ubiquitin C‐terminal hydrolase‐L1 (UCHL1) for motor neuron circuitry and especially in spinal motor neuron (SMN) health, function, and connectivity. METHODS: Since mutations in UCHL1 gene leads to motor dysfunction in patients, we inves...

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Detalles Bibliográficos
Autores principales: Genç, Barış, Jara, Javier H., Schultz, Megan C., Manuel, Marin, Stanford, Macdonell J., Gautam, Mukesh, Klessner, Jodi L., Sekerkova, Gabriella, Heller, Daniel B., Cox, Gregory A., Heckman, Charles J., DiDonato, Christine J., Özdinler, P. Hande
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863746/
https://www.ncbi.nlm.nih.gov/pubmed/27231703
http://dx.doi.org/10.1002/acn3.298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863746/
https://www.ncbi.nlm.nih.gov/pubmed/27231703
http://dx.doi.org/10.1002/acn3.298

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