Amitriptyline Activates TrkA to Aid Neuronal Growth and Attenuate Anesthesia-Induced Neurodegeneration in Rat Dorsal Root Ganglion Neurons

Tricyclic antidepressant amitriptyline (AM) has been shown to exert neurotrophic activity on neurons. We thus explored whether AM may aid the neuronal development and protect anesthesia-induced neuro-injury in young spinal cord dorsal root ganglion (DRG) neurons. The DRG explants were prepared from...

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Detalles Bibliográficos
Autores principales: Zheng, Xiaochun, Chen, Feng, Zheng, Ting, Huang, Fengyi, Chen, Jianghu, Tu, Wenshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
3300
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863790/
https://www.ncbi.nlm.nih.gov/pubmed/27149473
http://dx.doi.org/10.1097/MD.0000000000003559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863790/
https://www.ncbi.nlm.nih.gov/pubmed/27149473
http://dx.doi.org/10.1097/MD.0000000000003559

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