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MAP3K11/GDF15 axis is a critical driver of cancer cachexia

BACKGROUND: Cancer associated cachexia affects the majority of cancer patients during the course of the disease and thought to be directly responsible for about a quarter of all cancer deaths. Current evidence suggests that a pro‐inflammatory state may be associated with this syndrome although the m...

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Detalles Bibliográficos
Autores principales: Lerner, Lorena, Tao, Julie, Liu, Qing, Nicoletti, Richard, Feng, Bin, Krieger, Brian, Mazsa, Elizabeth, Siddiquee, Zakir, Wang, Ruoji, Huang, Lucia, Shen, Luhua, Lin, Jie, Vigano, Antonio, Chiu, M. Isabel, Weng, Zhigang, Winston, William, Weiler, Solly, Gyuris, Jeno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863827/
https://www.ncbi.nlm.nih.gov/pubmed/27239403
http://dx.doi.org/10.1002/jcsm.12077