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Dickkopf-3 is upregulated in osteoarthritis and has a chondroprotective role

OBJECTIVE: Dickkopf-3 (Dkk3) is a non-canonical member of the Dkk family of Wnt antagonists and its upregulation has been reported in microarray analysis of cartilage from mouse models of osteoarthritis (OA). In this study we assessed Dkk3 expression in human OA cartilage to ascertain its potential...

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Detalles Bibliográficos
Autores principales: Snelling, S.J.B., Davidson, R.K., Swingler, T.E., Le, L.T.T., Barter, M.J., Culley, K.L., Price, A., Carr, A.J., Clark, I.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders For The Osteoarthritis Research Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863878/
https://www.ncbi.nlm.nih.gov/pubmed/26687825
http://dx.doi.org/10.1016/j.joca.2015.11.021