Where, How, and When: Positioning Posttranslational Modification Within Type 1 Diabetes Pathogenesis

Autoreactive T cells specific for islet autoantigens develop in type 1 diabetes (T1D) by escaping central as well as peripheral tolerance. The current paradigm for development of islet autoimmunity is just beginning to include the contribution of posttranslationally modified (PTM) islet autoantigens...

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Detalles Bibliográficos
Autores principales: McLaughlin, Rene J., Spindler, Matthew P., van Lummel, Menno, Roep, Bart O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Immunology and Transplantation (L Piemonti and V Sordi, Section Editors)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863913/
https://www.ncbi.nlm.nih.gov/pubmed/27168063
http://dx.doi.org/10.1007/s11892-016-0752-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863913/
https://www.ncbi.nlm.nih.gov/pubmed/27168063
http://dx.doi.org/10.1007/s11892-016-0752-4

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