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Where, How, and When: Positioning Posttranslational Modification Within Type 1 Diabetes Pathogenesis
Autoreactive T cells specific for islet autoantigens develop in type 1 diabetes (T1D) by escaping central as well as peripheral tolerance. The current paradigm for development of islet autoimmunity is just beginning to include the contribution of posttranslationally modified (PTM) islet autoantigens...
Autores principales: | McLaughlin, Rene J., Spindler, Matthew P., van Lummel, Menno, Roep, Bart O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863913/ https://www.ncbi.nlm.nih.gov/pubmed/27168063 http://dx.doi.org/10.1007/s11892-016-0752-4 |
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