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Cancer Stem Cells in Small Cell Lung Cancer Cell Line H446: Higher Dependency on Oxidative Phosphorylation and Mitochondrial Substrate-Level Phosphorylation than Non-Stem Cancer Cells

Recently, targeting cancer stem cells (CSCs) metabolism is becoming a promising therapeutic approach to improve cancer treatment outcomes. However, knowledge of the metabolic state of CSCs in small cell lung cancer is still lacking. In this study, we found that CSCs had significantly lower oxygen co...

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Detalles Bibliográficos
Autores principales: Gao, Cuicui, Shen, Yao, Jin, Fang, Miao, Yajing, Qiu, Xiaofei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863974/
https://www.ncbi.nlm.nih.gov/pubmed/27167619
http://dx.doi.org/10.1371/journal.pone.0154576